Taiho Ventures, LLC

Preclinical to proof of concept.

Syndicate capital and operating partners for first-in-class therapeutics in oncology, immunology, and urology.

Mandate

We invest where the science is ready to be tested in patients.

Pre-IND through proof of concept. Oncology, immunology, urology. First-in-class molecules or new biology — not "me-too" programs targeting the same receptor with a different linker.

We syndicate, we operate, and where the asset earns it we underwrite a build-to-buy structure with our corporate parent — the same kind that built Cullinan Pearl from white paper through a Pfizer acquisition.

Portfolio

Twenty-three syndicate investments. Five clinical-stage assets. Four realized exits.

Open the portfolio

Cullinan Pearl

Oncology · Phase II · Bispecific Ab

Re-acquired by Taiho · 2023

Arcus Biosciences

Oncology · Phase III · Small molecule

NYSE: RCUS

Orna Therapeutics

Platform · Preclinical · Circular RNA

Merck partnership · 2023

Harpoon Therapeutics

Oncology · Phase I/II · T-cell engager

Acquired by Merck · 2024

Case Study

Build · Hold · Re-acquire

We led the build of Cullinan Pearl. We re-acquired it when the science was ready. Most of the work happened in the years between.

On Cullinan Pearl — Taiho Ventures × Cullinan Oncology, 2017–2024

Image Slot

1600×1000 · 8:5

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Editorial photo: Cullinan Pearl lab, team, or asset. Real, not stock.

Initial check
$8M · 2017 Series A lead
Re-acquisition
Taiho · 2023
Stage at exit
Phase II · zenocutuzumab
Read the Cullinan case study