$400M under management. Small molecules, biologics, and cell therapy — research through proof-of-concept. The corporate venture arm of Taiho Pharmaceutical.
The legacy mandate, restated. Four axes — what we invest in, who it treats, how it is built, when we come in. Each axis is locked. We do not drift.
Fig. 02.1
Sectors
First-in-class drug discovery and the platforms that produce it. Spin-outs from the Taiho pipeline. Devices, diagnostics, and digital health on an opportunistic basis.
·Drug discovery (first-in-class)
·Platform technologies
·Taiho pipeline spin-outs
·Device · diagnostic · digital (opportunistic)
Fig. 02.2
Therapeutic areas
Oncology is the center of the page. We keep a deliberate, smaller seat for non-oncology work — immunology, allergy, bone, muscle, orphan — where the science is unusually good.
·Oncology (primary)
·Immunology · allergy
·Bone · muscle
·Orphan indications
Fig. 02.3
Modality
Three families, weighted equally. We do not have a house bias toward small molecule or biologic; we follow the science.
·Small molecules
·Biologics
·Cell · gene therapy
Fig. 02.4
Stage
Research through proof-of-concept is most of what we do. Past the founding euphoria, before the Phase II answers are obvious. IND through PoC on an opportunistic basis.
·Research → pre-IND
·IND → proof-of-concept (opportunistic)
Plate 03 / Portfolio
Twenty-three companies. One syndicate at a time.
Most of these came to us in their second or third year — past the founding euphoria, before the answers were obvious. That is the moment we like best, and it is most of what we do.
Most of the companies on this page came to us in their second or third year — past the founding euphoria, before the answers were obvious. That is the moment we like best, and it is most of what we do.
Series A oncology rounds usually close on a thin stack of evidence and a thicker one of conviction; the work is helping a syndicate sort the two without flattening either. Ten years on, we measure the decade not by exits but by the partners we now call back first.