Two scientists in a working biotech lab reviewing data on a benchtop monitor.

TAIHO VENTURES, LLC

You’re working on the science Taiho has been working on.

A $400M corporate venture arm of Taiho Pharmaceutical, investing in early-stage companies in oncology, immunology, and urology — mostly research to pre-IND.

Taiho has been working on cancer, immunology, and urology for sixty years. The companies in this portfolio are working on what comes next — first-in-class small molecules, biologics, gene and cell therapy, mostly research to pre-IND. The check is the start of the conversation, not the end. Founders sit across from people who have actually taken a compound to approval, and the board seats we said we’d fill, we fill.

ABOUT TAIHO VENTURES

A corporate venture arm, run like a venture fund.

Two organizations, one operating history. The fund writes the check; the parent company provides the regulatory, clinical, and commercial muscle behind it.

The fund

Taiho Ventures, LLC

Taiho Ventures is the corporate venture arm of Taiho Pharmaceutical, a Japanese specialty pharmaceutical company in oncology, allergy and immunology, and urology. With $400M under management, we invest in early-stage private companies strategically relevant to Taiho.

We consider company creation, spin-outs, option-type investments, and pure equity rounds. Most checks are written at research to pre-IND; a few are written later when the science is right.

The parent

Taiho Pharmaceutical Co., Ltd.

Taiho Pharmaceutical, a subsidiary of Otsuka Holdings, is an R&D-driven specialty pharmaceutical company across oncology, allergy and immunology, and urology. Its corporate pledge: "We strive to improve human health and contribute to a society enriched by smiles."

In oncology, Taiho is a leading Japanese developer of innovative cancer medicines. Approved drugs are on the market across three continents, and the company has a sixty-year operating history behind it.

WHY PARTNER WITH US

A check, then a partner who has actually walked the regulatory path.

Operators on the cap table, not just capital.

You don’t get a check and a Slack channel. You get a partner who knows the regulatory path because they walked it — the people across the table from you have taken compounds through phase II, phase III, and to approval.

Patient capital from a sixty-year-old company.

Taiho is a privately-held subsidiary of Otsuka with no quarterly-earnings clock. The fund’s timeline is the science’s timeline. We can hold through a difficult clinical readout and follow on through the round you didn’t plan to need.

A commercial organization at the other end of the data.

Taiho has approved drugs on the market across three continents. When the data lands, you have a built-in conversation about co-development, licensing, or commercial partnership — with people who can actually pull the lever.

The board seats we said we’d fill, we fill.

No drive-by board members, no rotating cast. Whoever shows up to your first board meeting is the person who keeps showing up — through the next round, the next readout, and the next strategic decision.

WHERE WE INVEST

Areas of strategic alliance

Three therapeutic areas Taiho has been doing the work in for sixty years — plus the adjacent platforms that change what’s possible inside them.

  • Oncology

    Solid tumors, hematologic malignancies, and the targeted-therapy and ADC programs that come after them. The therapeutic area Taiho was founded on in 1963.

  • Immunology

    Autoimmune and inflammatory disease, with a working interest in the overlap with oncology — IO combinations, T-cell engagers, and the next wave of cell therapies.

  • Urology

    Genitourinary cancers and the broader urology pipeline. Less crowded than the headline indications, and an area where Taiho has been operating commercially for decades.

  • Adjacent platforms

    Gene and cell therapy, RNA, AI-led drug discovery, and the tooling underneath them. We back platforms when the science applies to a program we’d back on its own.

INVESTMENT CRITERIA

How we read a deck.

The short version of how we make decisions, by therapeutic area. The long version is on the criteria page, with the diligence questions we actually ask.

Therapeutic areaEntry stageInitial checkGeographyBoard involvementDetail link
OncologyResearch to pre-IND$3M–$15MUS, EU, JapanVoting seat or observerDetail
ImmunologyPre-IND to phase I$5M–$20MUS, EU, JapanVoting seatDetail
UrologyPre-IND to proof-of-concept$3M–$12MUS, EUVoting seat or observerDetail
Adjacent platformsSeed to series B$2M–$10MGlobalObserverDetail

WHO YOU WORK WITH

Five partners. All of them ex-Taiho operators.

The partnership is small on purpose. Whoever shows up to your first board meeting is the person who keeps showing up — through the next round, the next readout, and the next strategic decision.

  • Sakae Asanuma, CFA, MBA

    President & CEO

    Founded Taiho Ventures in 2016. Previously President & CEO at Astellas Venture Management. Has invested in 60+ biotech companies; the majority have reached IPO or M&A.

  • Seiji Miyahara, Ph.D.

    Partner & Senior Investment Director

    Eighteen years across life sciences R&D, company creation, and venture investment. Twelve of those years were at Taiho Pharmaceutical in oncology, advancing multiple programs into the clinic.

  • Takaaki Ishii

    Senior Investment Director

    Molecular biologist with 11+ years in oncology. Led the in-licensing of AB928 from Arcus Biosciences while at Taiho Pharmaceutical. Joined Taiho Ventures in 2019.

  • Hidefumi Kasuga, Ph.D.

    Investment Director

    Nine years at Taiho Pharmaceutical in EGFR-targeted oncology drug discovery. Earned his PhD in Pharmaceutical Science at the University of Tokyo. Joined Taiho Ventures in 2022.

  • Takayuki Hirano, Ph.D.

    Associate Investment Director

    Fifteen-plus years in non-clinical drug development, focused on toxicology and IND submissions for oncology compounds. Joined Taiho Ventures in 2024.

WHERE WE ARE

On Sand Hill Road, in Menlo Park.

Taiho Ventures, LLC

2420 Sand Hill Road, Suite 203
Menlo Park, CA 94025-6940

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